The star has given the full amount of his £25,000 award prize money to the MVT, which works to save the United Kingdom's grassroots music venues.
He was presented with the award on October 16 as his new release his work was chosen as the best record of the last 12 months.
He has chosen to give the cash to the Music Venues Trust, in appreciation of the essential function small stages fulfilled in his early career.
"As an artist couldn't be pursuing this success if it wasn't for all the performances I did around the area, and beyond, when I was beginning," said Sam Fender. "These venues are legendary, but they are facing challenges."
Since the start of 2023, over 150 of these locations have ceased operations – about 16% of the whole industry in the UK.
Recently, well-known musicians such as Pulp, Coldplay, Katy Perry and Ed Sheeran have all supported the trust in its initiatives to support the industry, by adding a minor surcharge to their ticket costs, which supports local stages.
Fender also took part, collecting in excess of £100,000 on his 2024 arena tour to assist numerous grassroots venues across Britain.
The donation helped spaces that were confronting imminent closure due to difficulties arising from flooding, fire incidents and bereavements, as well as regulatory hurdles, conflicts and noise complaints.
Other venues obtained funding support in improving facilities and sound and lighting systems that directly benefitted musicians and concertgoers.
"The notion that money from concerts in big venues helps the independent spots, where it kicks off for artists like me, is just logical," Sam Fender has said.
The musician is among several artists to donate his Mercury Prize funds to good deeds.
Back when the band won the award in the mid-90s for their release the album, vocalist the singer announced that the group would contribute their cash to the non-profit the charity.
In 2002, rapper and singer the artist split her award across multiple good causes, including the NSPCC and a Sickle Cell charity.
"I also gave a grand to Highgate Newtown, to their classes, because I trained in gymnastics when I was younger and they lacked updated gear," Ms Dynamite shared with a publication.
In recent years, the band contributed their prize money to the youth organization that supported their group, in addition to other independent music bodies.
Also the 1994 recipients they donated their winnings to a MS organization after a acquaintance was diagnosed the condition.
"The victory was ample," said vocalist Small. "The money was the bonus but we didn't require the cherry, because we had the cake. So our success impacted another person's life."
In the past week, the trust announced it had rescued a couple of local spots in the South East, by transferring them to local control.
One venue in Southampton and the second in Bristol were purchased under the public acquisition scheme, which is funded by the arts council and enthusiasts who acquire "shares" in the venues.
